Engine follows Jiro Kanzaki, a former Formula One racer who returns to Japan after his team in Europe is dissolved. Struggling to find his place in the professional racing world again, he finds himself working at 'Kaze no Oka,' a children's home run by his former mentor. Initially reluctant to engage with the children, Jiro is forced to confront his own past and lack of direction as he navigates the complex lives of the kids living there. As Jiro becomes more involved in the daily struggles of the children, he begins to rediscover his passion for life and racing. The series explores themes of resilience, the importance of family, and the courage required to pursue one's dreams despite setbacks. Through his interactions with the children and the staff, Jiro learns that the most important races are not always on the track, but in the connections we build with others.